Pharmint

active pharmaceutical ingredients (APIs)

Hydrochloride vs Free-Base

Hydrochloride Vs Free-Base – Differences, Benefits & Uses

How does your choice between a hydrochloride salt and its free-base counterpart impact drug formulation success – and your bottom line? Key Takeaways: Hydrochloride Vs Free-Base The main difference between hydrochloride salt and free-base forms is solubility: hydrochloride salts are ionized and water-soluble, while free-bases are uncharged and more lipid-soluble. Hydrochloride salts usually provide better stability, […]

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Tariffs Disrupt Cross-Border B2B Pharmaceutical Supply Chains

How Global Tariffs Disrupt B2B Pharma Trade and What Buyers Can Do?

“What happens when new trade taxes instantly raise the price of medicines worldwide?” In 2025, US  President Donald Trump announced steep tariffs on imported pharmaceuticals, APIs, and medical devices from countries including China, the Middle East, Africa, and India, a move aimed at boosting domestic manufacturing capacity (Source).  While the policy seeks to strengthen local

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