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N-Acetyl-D-Mannosamine cas 7772-94-3 precursor for synthesizing N-acetylneuraminic acid

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N-Acetyl-D-mannosamine (ManNAc) is a naturally occurring sugar (hexosamine) and a vital precursor for sialic acid (Neu5Ac)a key component of glycoproteins on cell surfaces, crucial for cell signaling, immunity, and viral interactions. Used in research and potential therapies, ManNAc helps synthesize sialic acid, supports immune function, and shows promise for neurological conditions like GNE myopathy, offering new avenues in medicine and biotech for enhancing drug delivery or combating diseases. 

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CAS Number: 7772-94-3

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Description

1. Biopharmaceuticals (Core Applications)

a. Drug Raw Materials: Serves as a direct precursor for synthesizing sialic acid (N-acetylneuraminic acid), used in the preparation of intermediates for anti-influenza and anti-inflammatory drugs.

b. Rare Disease Treatment: Applied in the development of drugs for treating mucopolysaccharidosis type IIIB (Sanfilippo B syndrome) by supplementing key metabolites deficient in patients, thereby slowing disease progression.

c. Immunomodulation and Antiviral Applications: Research indicates it can enhance immune cell activity, aiding in the development of antiviral agents (e.g., drugs targeting respiratory viruses and herpes viruses).

d. Cell Signaling Research: Functions as a tool molecule for exploring the effects of glycosylation modifications on cell signaling and tumor metastasis, supporting targeted drug development.

2. Food and Health Supplements

a. Functional Nutritional Fortifier: Added to infant formula and health products for middle-aged and elderly individuals to promote endogenous sialic acid synthesis, supporting brain development and immune enhancement.

b. Anti-Aging Health Product Ingredient: Marketed for “improving cellular glycosylation and delaying aging,” formulated into oral solutions, chewable tablets, and other products tailored for anti-aging consumers.

c. Gut Health Products: Serves as an auxiliary ingredient in gut health supplements by regulating gut microbiota balance and promoting intestinal mucosal barrier repair.

3. Cosmetics

a. Anti-Aging and Repair Ingredient: Promotes the synthesis of skin cell surface glycoproteins, enhances skin barrier function, reduces fine lines and dryness, and is incorporated into creams and serums.

b. Moisturizing and Anti-Inflammatory Properties: Exhibits excellent water solubility and moisturizing capacity while soothing skin inflammation, making it suitable for anti-aging and repair products for sensitive skin.

c. Hair Care Component: Modifies the glycosylation structure of hair keratin, improving hair smoothness and strength, and is used in high-end shampoos and hair care oils.

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