(S)-1-(3-Bromopyridin-2-yl)ethan-1-ol cas 317845-81-1 Pharmaceutical Intermediate

1. Pharmaceutical Field (Core Applications)

a. Pharmaceutical Intermediate: Used in the synthesis of pyridine-based targeted drugs, including antitumor agents (e.g., EGFR inhibitors), antibacterial drugs, and antiviral drugs. Its chiral structure and pyridine ring enhance the specificity of drug-target binding.

b. Drug Molecular Modification: Through derivatization reactions involving hydroxyl and bromine groups, it optimizes drug solubility, lipophilicity, and metabolic stability, thereby improving efficacy and reducing side effects.

c. Peptide and Small-Molecule Drug Construction: Serves as a chiral building block in the synthesis of heterocyclic peptide mimetics and alkaloid drugs, enriching the structural diversity of drug molecules.

2. Fine Chemical Industry

a. Chiral Synthesis Reagent: Functions as a chiral source in asymmetric synthesis for producing optically pure intermediates for dyes and fragrances. Its chiral hydroxyl group enables directional introduction into target molecules.

b. Organic Functional Material Precursor: Utilizes the coordination of pyridine rings with metal ions to prepare chiral catalysts and optically active polymer materials, meeting the needs for specialized functional materials.