Mesalamine works by reducing inflammation in the intestines, which helps to alleviate symptoms such as diarrhea, abdominal pain, and rectal bleeding. The medication is available in several different forms, including oral tablets, capsules, and extended-release tablets, as well as rectal suppositories and enemas.
The exact mechanism of action of mesalamine is not fully understood, but it is believed to work by inhibiting the production of inflammatory chemicals in the body, such as prostaglandins and leukotrienes. Mesalamine may also have antioxidant properties that help to protect the intestinal lining from damage.