It is important clinically the determination of chloride due regulation of osmotic pressure of extra cellular fluid and to its significant role in acid-base balance. Increases in chloride ion concentration may be found in severe dehydratation, excessive intake of chloride, severe renal tubular damage and in patients with cystic fibrosis. Decrease in chloride ion concentration may be found in metabolic acidosis, loss from prolonged vomiting and chronic pyelonephritis. Clinical diagnosis should not be made on a single test result; it should integrate clinical and other laboratory data.
STORAGE AND STABILITY 0 All reagents are stable at R.T. (25 C) till the expiry date mentioned on the labels
SPECIMEN Serum /Heparinised plasma /urine /CSF. Urine specimen should be diluted 1+1 with distilled water (multiply result with 2)
