The “N’-4-acetyl” part of the name “Gemcitabine N’-4-Acetyl cytosine” refers to a metabolite of gemcitabine that is produced in the body. This metabolite is known as 4-amino-2-(4-acetamido-2-oxopyrimidin-1-yl)butanoic acid, and it is formed when gemcitabine is broken down in the body.
Gemcitabine is generally well-tolerated, but it can cause side effects, including nausea, vomiting, fatigue, and low blood cell counts. If you are being treated with gemcitabine, it is important to discuss any side effects you experience with your doctor, as they may be able to recommend treatments to help manage them