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2,4-DICHLORO-5-NITROPYRIMIDINE-49845-33-2

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2,4-Dichloro-5-nitropyrimidine, also known as DCNP, is a chemical compound with the molecular formula C5H2Cl2N2O2.

DCNP is a potent and selective inhibitor of protein kinase CK2, an enzyme that is involved in the regulation of many cellular processes, In addition to its use as a CK2 inhibitor, DCNP has also been used in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. For example, DCNP is a key intermediate in the synthesis of the antiviral drug acyclovir.

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Description

DCNP has been used in preclinical research for its anticancer and antiviral properties. Some studies have shown that DCNP inhibits the growth of various cancer cell lines, including melanoma, breast cancer, and prostate cancer. DCNP has also been investigated for its potential antiviral effects against human immunodeficiency virus (HIV) and herpes simplex virus (HSV).

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