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About API Sotorasib:

Sotorasib is indicated for adults with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC) who have previously received at least one systemic treatment. This subtype of NSCLC is driven by a KRAS G12C gene alteration that affects cellular growth and proliferation and is present in approximately 11–15% of cases. The identification of this mutation has enabled the use of targeted therapies, expanding treatment options for eligible patients.