Aluminum hydroxide adjuvant

Alhydrogel 2% has worldwide acceptance and it is used in many vaccines. Alhydrogel is the standard preparations for immunological research on aluminum hydroxide gels. The use of aluminum adjuvants is accompanied by stimulation of IL-4 and stimulation of the T-helper-2 subsets in mice, with enhanced IgG1 and IgE production. Aluminum hydroxide gel is obtained by precipitation of aluminum hydroxide Al(OH)3 under alkaline conditions. It is currently used as an adjuvant in subunit, DNA and conjugate vaccines.