8-BROMO-7-(BUT-2-YNYL)-3-METHYL-3,7- DIHYDROPURINE-2,6-DIONE- 666816-98-4

The chemical compound 8-Bromo-7-(but-2-ynyl)-3-methyl-3,7-dihydropurine-2,6-dione, with the CAS number 666816-98-4, is a purine derivative with potential pharmaceutical applications.

This compound has been investigated for its potential as a selective inhibitor of the enzyme phosphodiesterase 5 (PDE5), which plays a key role in the regulation of smooth muscle tone in the lungs and blood vessels. Inhibition of PDE5 can lead to increased blood flow, making PDE5 inhibitors potential treatments for conditions such as pulmonary arterial hypertension and erectile dysfunction.

8-Bromo-7-(but-2-ynyl)-3-methyl-3,7-dihydropurine-2,6-dione has also been studied for its potential as an anti-inflammatory agent, as it has been shown to inhibit the production of certain pro-inflammatory cytokines.