SEROMAX WIDAL (OH)

Salmonella typhi is the causative agent of “Enteric Fever”. In Enteric Fever once the patient is on medication it becomes difficult to isolate the organisms. In serological tests the antibodies produced as a result of infection are detected by using the killed and Inactivated bacterialantigens. The antibodies from the patient’s serum react with the corresponding antigens to give clumping or agglutination. The antigens of Typhoid consist of two distinct fractions. The Stable Somatic ‘O’Antigen and the Labile Flagellar ‘H’ Antigen. In Typhoid the ‘H’ Antigen is Type Specific, whereas the ‘O’ Antigen is Group Specific. SeroMAX WIDAL (OH) Antigens are stabilized smooth suspensions of killed and inactivated bacterial antigens for Qualitative and Semiquantitative Detection of S. Typhi antibodies. The different color given to each Antigen facilitates the differentiation. It also avoids the possible errors of misinterpretation. As the undiluted serum is used in Slide Test, it is a Simple, Rapid and Convenient Screening Test. The slide test antigens are standardized to be used for either the Slide or Tube Technique. In doubtful cases, it is recommended to perform the tube technique to obtain conclusive results. A marked rise in the titre to one Serotype (above 1:80) suggests infection. Diagnostically a rising antibody titre of at least four folds (two tube difference) is considered more significant than a single test. It is observed that individuals immunized with TAB vaccine may show a moderately high titre for all the Antigens.