{"id":1747470,"date":"2026-01-10T17:32:46","date_gmt":"2026-01-10T12:02:46","guid":{"rendered":"https:\/\/pharmint.net\/?post_type=product&p=1747470"},"modified":"2026-01-10T17:43:45","modified_gmt":"2026-01-10T12:13:45","slug":"phospholipase-d-4","status":"publish","type":"product","link":"https:\/\/pharmint.net\/zh\/product\/phospholipase-d-4\/","title":{"rendered":"Phospholipase D"},"content":{"rendered":"

1. Biopharmaceuticals and Medical Field<\/p>\n

a. Drug Development Tool: Used for studying cell signaling pathways (e.g., phosphatidylinositol signaling pathways), aiding in research on the pathogenesis of diseases such as tumors and inflammation.<\/p>\n

b. Nucleic Acid Delivery Vehicle Preparation: Modifies the surface of liposomes through PLD-catalyzed transphosphatidylation reactions, enhancing the delivery efficiency and targeting of nucleic acid drugs (e.g., mRNA vaccines, siRNA).<\/p>\n

c. Diagnostic Reagent Raw Material<\/a>: Serves as a tool enzyme for in vitro diagnostics of phospholipid metabolism-related diseases, assisting in detecting liver function and cardiovascular disease markers.<\/p>\n

2. Food Industry Field<\/p>\n

a. Food Additive Production: Produces phosphatidylserine, catalyzes phospholipid modification, and manufactures food emulsifiers such as lysophospholipids and functional phospholipids to improve food texture, stability, and shelf life.<\/p>\n

b. Oil Refining: Used to remove phospholipid impurities from oils (degumming), enhancing the purity and quality of edible oils and reducing the generation of harmful substances in subsequent processing.<\/p>\n

c. Dairy Product Improvement: Added to dairy products to regulate milk fat structure, enhancing emulsification stability and nutritional value.<\/p>\n

3. Cosmetics Field<\/p>\n

a. Skincare Ingredient: Catalyzes the synthesis of ceramide precursors from phospholipids, helping repair the skin barrier and improve conditions of dryness and sensitivity, and is added to moisturizing creams and repair serums.<\/p>\n

b. Hair Care Component: Modifies the lipid layer on the hair surface, enhancing smoothness and damage resistance, and is used in shampoo and conditioner formulations.<\/p>\n

4. Biochemical Engineering Field<\/p>\n

a. Biodiesel Production: Catalyzes the transesterification of vegetable oils or animal fats to efficiently synthesize biodiesel, reducing the stringency of reaction conditions (e.g., enabling reactions at low temperatures and pressures).<\/p>\n

b. Functional Phospholipid Synthesis: Utilizes transphosphatidylation reactions to directionally synthesize high-value special phospholipids (e.g., phosphatidylserine, phosphatidylethanolamine) for use in health products and pharmaceutical excipient<\/a>s.<\/p>\n

c. Biosensor Construction: Immobilized PLD serves as a biological recognition element to develop biosensors for detecting phospholipids and choline-based substances, applied in environmental monitoring and food testing.<\/p>","protected":false},"excerpt":{"rendered":"

Phospholipase D (PLD) is\u00a0a crucial enzyme that hydrolyzes\u00a0phosphatidylcholine\u00a0(PC) to produce\u00a0phosphatidic acid\u00a0(PA) and choline, acting as a key regulator in signal transduction, membrane trafficking, cytoskeletal dynamics, and cell proliferation in organisms from bacteria to mammals. PA itself is a vital lipid second messenger, which can be further converted to other signaling molecules like\u00a0<\/span>diacylglycerol\u00a0(DAG) and\u00a0<\/span>lysophosphatidic acid\u00a0(LPA), influencing pathways like PKC, PI3K\/Akt, and mTOR, and playing roles in development, cancer, and neurological disorders.<\/span>\u00a0<\/span><\/span><\/span><\/p>","protected":false},"featured_media":1747472,"comment_status":"open","ping_status":"closed","template":"","meta":{"rank_math_lock_modified_date":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"product_cat":[766],"product_tag":[2312,2311],"class_list":{"0":"post-1747470","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-chemical-compound-2","7":"product_tag-phospholipase-d","8":"product_tag-pld","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","12":"ast-product-gallery-layout-vertical","13":"ast-product-gallery-with-no-image","14":"ast-magnify-disabled","15":"ast-product-tabs-layout-distributed","17":"first","18":"instock","19":"shipping-taxable","20":"purchasable","21":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/product\/1747470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/comments?post=1747470"}],"version-history":[{"count":2,"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/product\/1747470\/revisions"}],"predecessor-version":[{"id":1747473,"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/product\/1747470\/revisions\/1747473"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/media\/1747472"}],"wp:attachment":[{"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/media?parent=1747470"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/product_cat?post=1747470"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pharmint.net\/zh\/wp-json\/wp\/v2\/product_tag?post=1747470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}