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N,N’-Diisopropylcarbodiimide (DIC) is a chemical compound with the molecular formula C8H16N2. Its CAS number is 693-13-0.

DIC is a commonly used coupling agent in organic synthesis, particularly in peptide synthesis. It is used to activate carboxylic acids for amide bond formation in the presence of amines or amino acids. DIC is a highly reactive and efficient coupling agent that can promote rapid and quantitative formation of amide bonds.

DIC is also used as a dehydrating agent and as a catalyst in a variety of organic reactions, including esterification, transesterification, and acylation reactions.