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15,7-TRIAZABICYCLO[4.4.2]DEC-5-ENE 5807-14-7

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1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) is widely used as a catalyst in the pharmaceutical industry for the synthesis of various drugs and active pharmaceutical ingredients (APIs). It is particularly useful in the synthesis of amides, esters, and lactones.

TBD has been utilized in the synthesis of a number of drugs, including anti-inflammatory agents, antiviral drugs, and anticancer drugs. For example, TBD has been used as a catalyst in the synthesis of acyclovir, an antiviral medication used to treat herpes simplex virus infections, and celecoxib, a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation.

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