{"id":20027,"date":"2022-10-20T12:47:36","date_gmt":"2022-10-20T04:47:36","guid":{"rendered":"https:\/\/pharmint.xyz\/?post_type=product&#038;p=20027"},"modified":"2025-08-05T17:02:07","modified_gmt":"2025-08-05T11:32:07","slug":"fexofenadine-hydrochloride","status":"publish","type":"product","link":"https:\/\/pharmint.net\/es\/product\/fexofenadine-hydrochloride\/","title":{"rendered":"Fexofenadine Hydrochloride"},"content":{"rendered":"<h2 style=\"text-align: center;\"><a href=\"https:\/\/pharmint.net\/product\/fexofenadine-hydrochloride\/\" target=\"_blank\" rel=\"noopener\"><strong>Fexofenadine Hydrochloride (CAS No. 83799-24-0) &ndash; Non-Sedating Antihistaminic API&nbsp;<\/strong><\/a><\/h2>\n<h3 style=\"text-align: center;\"><strong>GMP API Supplier for Allergy Formulations<\/strong><\/h3>\n<p><strong>Fexofenadine<\/strong>&nbsp;is a&nbsp;<strong>selective H1-antagonist<\/strong>&nbsp;and&nbsp;<strong>an antihistamine medication used in the treatment of allergy symptoms<\/strong>, including&nbsp;<strong>seasonal allergic rhinitis<\/strong>&nbsp;and&nbsp;<strong>chronic urticaria<\/strong>. As a&nbsp;<strong>second-generation antihistaminic medication<\/strong>, it offers targeted H1 receptor blockade with minimal central nervous system penetration&mdash;ideal for formulating&nbsp;<strong>non-drowsy<\/strong>&nbsp;antihistamine tablets and suspensions.<\/p>\n<p>It is also the&nbsp;<strong>active pharmaceutical ingredient (API)<\/strong>&nbsp;in branded products like&nbsp;<strong>Allegra<\/strong>.<\/p>\n<h3><strong>How Is Fexofenadine Used in Pharmaceutical Manufacturing?<\/strong><\/h3>\n<p><strong>Fexofenadine is an antihistamine medicine that relieves the symptoms of allergies<\/strong>, commonly formulated into:<\/p>\n<ul>\n<li>Oral solid dosage forms (<strong>one tablet [180 mg] daily<\/strong>)<\/li>\n<li>Pediatric suspensions<\/li>\n<li>Non-sedating antihistamine syrups<\/li>\n<li>Generic versions of Allegra&reg;<\/li>\n<\/ul>\n<p>It is widely used by&nbsp;<strong>OTC drug manufacturers<\/strong>,&nbsp;<strong>formulators<\/strong>, and&nbsp;<strong>R&amp;D labs<\/strong>&nbsp;targeting&nbsp;<strong>seasonal allergic rhinitis<\/strong>&nbsp;and&nbsp;<strong>chronic idiopathic urticaria<\/strong>.<\/p>\n<h3><strong>Why Do B2B Buyers Choose Pharmint for Fexofenadine Supply?<\/strong><\/h3>\n<p>Pharmint delivers&nbsp;<strong>GMP-compliant Fexofenadine Hydrochloride in bulk<\/strong>, with advantages tailored to international procurement:<\/p>\n<ul>\n<li>COA\/MSDS included for every batch<\/li>\n<li>Scalable supply from kilos to metric tons<\/li>\n<li>Regulatory-ready documentation:&nbsp;<strong>DMF support<\/strong>,&nbsp;<strong>HS Code: 29333990<\/strong><\/li>\n<li>Export-compliant with&nbsp;<strong>end-use declaration requirements<\/strong><\/li>\n<\/ul>\n<h3><strong>What Are the Technical &amp; Quality Specifications?<\/strong><\/h3>\n<table>\n<tbody>\n<tr>\n<td><strong>Parameter<\/strong><\/td>\n<td><strong>Specification<\/strong><\/td>\n<\/tr>\n<tr>\n<td><strong>CAS Number<\/strong><\/td>\n<td>83799-24-0<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Formula<\/strong><\/td>\n<td>C32H39NO4&middot;HCl<\/td>\n<\/tr>\n<tr>\n<td><strong>Appearance<\/strong><\/td>\n<td>White to off-white crystalline<\/td>\n<\/tr>\n<tr>\n<td><strong>Purity (HPLC)<\/strong><\/td>\n<td>&ge; 99%<\/td>\n<\/tr>\n<tr>\n<td><strong>Half-life<\/strong><\/td>\n<td>~14 hours<\/td>\n<\/tr>\n<tr>\n<td><strong>Metabolism<\/strong><\/td>\n<td>Minimal, largely excreted unchanged<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>How Is This Antihistamine Packaged and Shipped for Bulk Orders?<\/strong><\/h3>\n<ul>\n<li><strong>Standard Packaging<\/strong>: HDPE drums or fiberboard with foil liners<\/li>\n<li><strong>Storage<\/strong>: Cool, dry, light-protected areas<\/li>\n<li><strong>Shipping<\/strong>: Export-ready with full documentation, REACH pre-registration<\/li>\n<li><strong>Use Restriction<\/strong>:&nbsp;<strong>For research or industrial formulation only<\/strong>, not for human use<\/li>\n<\/ul>\n<h3><strong>What Makes Fexofenadine Ideal for OTC and Generic Products?<\/strong><\/h3>\n<p>Because&nbsp;<strong>Fexofenadine is an antihistamine that is taken to help treat allergy symptoms<\/strong>&nbsp;without causing drowsiness, it is ideal for:<\/p>\n<ul>\n<li>Daytime allergy medications<\/li>\n<li>Fast-acting formulations<\/li>\n<li>Pediatric-safe compounds (per region-specific guidance)<\/li>\n<li>Markets requiring minimal CNS side effects<\/li>\n<\/ul>\n<h2><strong>Fexofenadine Hydrochloride FAQs<\/strong><\/h2>\n<h4><strong>Can Fexofenadine Hydrochloride be used in effervescent or fast-dissolving tablet formulations?<\/strong><\/h4>\n<p>Fexofenadine Hydrochloride supports modified-release forms due to its stability and solubility profile, making it compatible with effervescent and fast-dissolving delivery systems for improved patient compliance.<\/p>\n<h4><strong>What particle size distribution is typically required for tablet-grade Fexofenadine API?<\/strong><\/h4>\n<p>Tablet-grade Fexofenadine often requires D90 &le; 150 &mu;m for uniform blending and compressibility, ensuring consistent dosing and content uniformity in solid dosage forms.<\/p>\n<h4><strong>Is Fexofenadine Hydrochloride stable under high humidity or temperature conditions?<\/strong><\/h4>\n<p>Fexofenadine exhibits hygroscopic sensitivity; optimal storage is in sealed, moisture-resistant containers under 25&deg;C to maintain stability during transport and storage.<\/p>\n<h4><strong>Can Fexofenadine be co-formulated with decongestants or corticosteroids?<\/strong><\/h4>\n<p>Yes, Fexofenadine is often co-formulated with pseudoephedrine or intranasal corticosteroids in fixed-dose combinations for synergistic allergy symptom control in multi-symptom OTC products.<\/p>\n<h4><strong>Does Fexofenadine require any specific granulation technique during tableting?<\/strong><\/h4>\n<p>Due to its poor flow properties, Fexofenadine may benefit from wet granulation or direct compression with <a href=\"https:\/\/pharmint.net\/es\/glossary\/excipient\/\" target=\"_self\" title=\"What is an Excipient? An&nbsp;excipient&nbsp;is an inactive substance used alongside the Active Pharmaceutical Ingredient (API) in a pharmaceutical formulation. Though excipients have no therapeutic effect, they play essential roles in drug delivery, stability, solubility, taste masking, and manufacturing processability. They are chemically stable and pharmaceutically inert but must meet stringent quality and safety standards. Why&hellip;\" class=\"encyclopedia\">excipient<\/a>s enhancing flowability and compactability for scalable manufacturing.<\/p>","protected":false},"excerpt":{"rendered":"<p>Fexofenadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes\/nose, sneezing, hives, and itching.<\/p>","protected":false},"featured_media":29630,"comment_status":"open","ping_status":"closed","template":"","meta":{"rank_math_lock_modified_date":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"product_cat":[298,303,53],"product_tag":[],"class_list":{"0":"post-20027","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-common-disease-medicine","7":"product_cat-pharmaceutical-drug","8":"product_cat-tablet","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","12":"ast-product-gallery-layout-vertical","13":"ast-product-gallery-with-no-image","14":"ast-magnify-disabled","15":"ast-product-tabs-layout-distributed","17":"first","18":"instock","19":"shipping-taxable","20":"purchasable","21":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product\/20027","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/comments?post=20027"}],"version-history":[{"count":2,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product\/20027\/revisions"}],"predecessor-version":[{"id":1738761,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product\/20027\/revisions\/1738761"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/media\/29630"}],"wp:attachment":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/media?parent=20027"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product_cat?post=20027"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product_tag?post=20027"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}