Alanine aminotransferase (glutamate-pyruvate-transaminase) belongs to the group of transaminases which catalyze the conversion of amino acids to the corresponding á-keto acids via the transfer of amino groups; they also catalyze the reverse process. Although higher activities exist in the liver, minor activity can also be detected in the kidneys, heart, skeletal muscle, pancreas, spleen, and lungs. Elevated levels of transaminases are indicative of myocardial infarction, hepatopathies, muscular dystrophy, and damage to internal organs. Increased ALT activity in the serum, however, is a rather specific indicator of damage to the liver parenchyma, while AST is not necessarily a liver-specific parameter. In 1956, Wroblewski and LaDue described the first kinetic determination of ALT in serum. In 1977 and 1980, the International Federation of Clinical Chemistry (IFCC) recommended standardized methods for the determination of ALT with optimized substrate concentrations. The method described here is derived from the IFCC reference method. *TRIS = Tris(hydroxymethyl)-aminomethane<\/p>","protected":false},"excerpt":{"rendered":"
INTENDED USE: In vitro test for the quantitative determination of Alanine Aminotransferase (ALT) in human
\nserum and plasma.
\nP R O D U C T F E A T U R E S :
\n1. Two Liquid Reagents (4 parts of R1 + 1 part of R2).
\n2. Working reagent stability of 60 days at 2-8\u00b0 C.
\n3. Linearity 500 IU\/L.
\n4. Kinetic reaction time 4 minutes.
\n5. Kinetic factor 1746 at 340 nm at 37\u00b0 C.
\n6. Measuring wavelength 340 nm.
\n7. Tailor made for tropical Conditions.
\n8. Incorporates Six Sigma methodologies throughout the manufacturing processes where in the
\nproduct under goes various stringent process checks like Defining, Measuring, Analyzing,
\nImproving and Controlling. (DMAIC)
\n9. No interference was observed by ascorbic acid up to 32 mg\/dl, bilirubin up to 43 mg\/dl,
\nhaemoglobin up to 500 mg\/dl and lipemia up to 2200 mg\/dl.
\n10 Can be used on any discrete semi-automated and automated analyzers.
\n11. User friendly pack sizes (5 x 10ml, 4 x 25ml,10 x 25ml, 20 x 25ml).
\nan be used on any discrete semi automated and automated analyzer<\/p>","protected":false},"featured_media":9988,"comment_status":"open","ping_status":"closed","template":"","meta":{"rank_math_lock_modified_date":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"product_cat":[112],"product_tag":[154],"class_list":{"0":"post-10001","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-others","7":"product_tag-reagent-kit","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","11":"ast-product-gallery-layout-vertical","12":"ast-magnify-disabled","13":"ast-product-tabs-layout-distributed","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product\/10001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/comments?post=10001"}],"version-history":[{"count":0,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product\/10001\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/media\/9988"}],"wp:attachment":[{"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/media?parent=10001"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product_cat?post=10001"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pharmint.net\/es\/wp-json\/wp\/v2\/product_tag?post=10001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}