{"id":188466,"date":"2023-05-11T20:21:54","date_gmt":"2023-05-11T14:51:54","guid":{"rendered":"https:\/\/pharmint.co\/product\/nicotine-3\/"},"modified":"2025-08-07T20:26:21","modified_gmt":"2025-08-07T14:56:21","slug":"nicotine-3","status":"publish","type":"product","link":"https:\/\/pharmint.net\/ar\/product\/nicotine-3\/","title":{"rendered":"Nicotine"},"content":{"rendered":"<h2 style=\"text-align: center;\"><a href=\"https:\/\/pharmint.net\/product\/nicotine-3\/\"><strong>Nicotine (CAS: 54-11-5)<\/strong><\/a><\/h2>\n<h4 style=\"text-align: center;\"><strong>GMP-Grade API for NRT and QC Applications<\/strong><\/h4>\n<p>Nicotine (3&#8209;[(2S)&#8209;1&#8209;methylpyrrolidin&#8209;2&#8209;yl]pyridine) is a plant-derived alkaloid and the&nbsp;<strong>core API used in nicotine replacement therapies (NRT)<\/strong>&nbsp;such as gums, patches, lozenges, and inhalation products. Our offering includes&nbsp;<strong>high-purity, pharmaceutical-grade Nicotine<\/strong>, available in both standard and customized bulk quantities with full regulatory documentation.<\/p>\n<p>Backed by stringent manufacturing standards, Pharmint provides nicotine conforming to global pharmacopeial monographs&mdash;<strong>USP, EP, JP<\/strong>&mdash;ensuring consistency, safety, and audit-readiness across regulated markets.<\/p>\n<h3><strong>Where is Nicotine Used in Pharma and R&amp;D?<\/strong><\/h3>\n<h5><strong>&#10004; Nicotine Replacement Therapy (NRT)<\/strong><\/h5>\n<p>Pharmint supplies nicotine in GMP-grade quality, designed for therapeutic use in smoking cessation products such as:<\/p>\n<ul>\n<li>Nicotine patches (transdermal systems)<\/li>\n<li>Chewing gums and oral strips<\/li>\n<li>Nasal sprays and inhalers<\/li>\n<\/ul>\n<h5><strong>&#10004; Analytical Method Development &amp; Quality Control<\/strong><\/h5>\n<p>We also supply&nbsp;<strong>analytical-grade (S)-Nicotine<\/strong>&nbsp;suitable for:<\/p>\n<ul>\n<li>Chromatographic method validation<\/li>\n<li>Stability testing<\/li>\n<li>Internal standard use in regulatory submissions<\/li>\n<\/ul>\n<h5><strong>&#10004; R&amp;D and Custom Formulations<\/strong><\/h5>\n<p>For laboratories and CDMOs developing novel NRT delivery systems, we offer&nbsp;<strong>custom packaging, small-batch lots, and R&amp;D documentation support<\/strong>.<\/p>\n<h3><strong>Technical Specifications<\/strong><\/h3>\n<table>\n<tbody>\n<tr>\n<td><strong>Property<\/strong><\/td>\n<td><strong>Value<\/strong><\/td>\n<\/tr>\n<tr>\n<td>CAS Number<\/td>\n<td>54-11-5<\/td>\n<\/tr>\n<tr>\n<td>Molecular Formula<\/td>\n<td>C10H14N2<\/td>\n<\/tr>\n<tr>\n<td>Molecular Weight<\/td>\n<td>162.23 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>Enantiomeric Purity<\/td>\n<td>(S)-Isomer predominant<\/td>\n<\/tr>\n<tr>\n<td>Physical State<\/td>\n<td>Colorless to pale yellow liquid<\/td>\n<\/tr>\n<tr>\n<td>Solubility<\/td>\n<td>Soluble in alcohol, ether<\/td>\n<\/tr>\n<tr>\n<td>Flash Point<\/td>\n<td>95&deg;C<\/td>\n<\/tr>\n<tr>\n<td>Density<\/td>\n<td>~1.01 g\/cm&sup3;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>Why Source Nicotine from Pharmint?&nbsp;<\/strong><\/h3>\n<h4><strong>&#9989; Full Regulatory Support<\/strong><\/h4>\n<p>We understand the rigorous documentation needs of regulated markets. Each nicotine batch is shipped with:<\/p>\n<ul>\n<li>GMP Certificate<\/li>\n<li>CoA (Certificate of Analysis)<\/li>\n<li>USDMF &amp; CEP support<\/li>\n<li>ICH Stability Data (on request)<\/li>\n<\/ul>\n<h4><strong>&#9989; Global Fulfillment &amp; Compliance<\/strong><\/h4>\n<ul>\n<li><strong>Export-ready<\/strong>&nbsp;with end-use declaration support<\/li>\n<li>Hazardous Goods shipping protocol (Class 6.1)<\/li>\n<li>Dedicated regulatory liaison for CEP\/DMF access<\/li>\n<\/ul>\n<h4><strong>&#9989; Flexible Supply Chain for Pharma Procurement<\/strong><\/h4>\n<ul>\n<li>MOQ starts from grams to multi-kilo bulk<\/li>\n<li>Cold-chain and compliance shipping<\/li>\n<li>White-label options for formulation partners<\/li>\n<\/ul>\n<h4><strong>&#9989; Trusted Manufacturing Provenance<\/strong><\/h4>\n<p>Sourced from&nbsp;<strong>GMP-audited production sites<\/strong>&nbsp;with CEP\/USDMF linkage&mdash;used by top NRT brands and formulation CDMOs across the U.S., EU, and Asia-Pacific.<\/p>\n<h3><strong>How Is Nicotine Packaged and Stored?<\/strong><\/h3>\n<ul>\n<li>Supplied in HDPE\/Amber glass with PTFE-lined closures<\/li>\n<li>Long-term storage: 15&ndash;30&#8239;&deg;C, protected from light<\/li>\n<li>Analytical standards available in 1&#8239;mg\/mL methanol solution with full SDS and TDS<\/li>\n<\/ul>\n<h3><strong>Is This Nicotine Suitable for International Export?<\/strong><\/h3>\n<p>Yes. Pharmint ensures:<\/p>\n<ul>\n<li><strong>Global export-readiness<\/strong>, with support for end-use declarations<\/li>\n<li><strong>Hazardous goods shipping compliance<\/strong>&nbsp;(UN1992, Class 6.1)<\/li>\n<li><strong>Labeling in line with GHS\/REACH\/CLP<\/strong><\/li>\n<\/ul>\n<h3><strong>Who Uses Pharmint&rsquo;s Nicotine?<\/strong><\/h3>\n<p>Our nicotine is trusted by:<\/p>\n<ul>\n<li>Global NRT brands for finished dosage formulation<\/li>\n<li>CDMOs for formulation and ANDA filings<\/li>\n<li>Analytical labs validating pharmacopeial methods<\/li>\n<\/ul>\n<h2><strong>Nicotine FAQs<\/strong><\/h2>\n<h4><strong>Can nicotine from Pharmint be used in regulated NRT products?<\/strong><\/h4>\n<p>Yes. Our nicotine meets GMP, USP, and EP standards, with CoA and full regulatory files (USDMF, CEP) to support registration in the U.S., EU, and Japan.<\/p>\n<h4><strong>What grade of nicotine is offered for QC and method development?<\/strong><\/h4>\n<p>We offer (S)-Nicotine as a certified <a href=\"https:\/\/pharmint.net\/ar\/glossary\/reference-standard\/\" target=\"_self\" title=\"A&nbsp;reference standard&nbsp;(or reference material) is a highly characterized substance used as a benchmark in pharmaceutical analytical testing&mdash;for identity, assay, or purity evaluations. It must be of sufficient quality for its purpose and may undergo additional characterization beyond routine testing.&nbsp; Why is a Reference Standard Critical in Pharmaceutical Analysis? Reference standards are the&nbsp;foundation of analytical consistency&hellip;\" class=\"encyclopedia\">reference standard<\/a> (&ge;99%) in both neat and methanolic solutions, with traceable purity, COA, and stability data.<\/p>\n<h4><strong>What regulatory documentation is included with bulk nicotine supply?<\/strong><\/h4>\n<p>We provide GMP Certificate, CoA, MSDS, and optional USDMF\/CEP access, tailored to the compliance needs of each buyer&rsquo;s market.<\/p>\n<h4><strong>Is this product REACH-registered or compliant for EU distribution?<\/strong><\/h4>\n<p>Our nicotine is compliant with REACH and CLP regulations, and can be shipped within the EU with appropriate safety labeling and transport classification.<\/p>\n<h4><strong>What is the standard lead time and MOQ for pharmaceutical nicotine?<\/strong><\/h4>\n<p>Typical <a href=\"https:\/\/pharmint.net\/ar\/glossary\/lead-time\/\" target=\"_self\" title=\"What Is Lead Time in Pharmaceutical Operations? Lead Time&nbsp;is the total duration from the initiation of a process (e.g., ordering materials) to its completion (e.g., receiving the finished product). This includes all steps from sourcing&nbsp;raw materials&nbsp;through manufacturing and&nbsp;quality control, to final delivery. Why Is Lead Time Important in Pharma? Operational Planning: Understanding lead times helps&hellip;\" class=\"encyclopedia\">lead time<\/a> is 7&ndash;14 days ex-stock; MOQ begins at 50 grams for R&amp;D and 1 kg for commercial NRT manufacturing, with scalable volume pricing.<\/p>","protected":false},"excerpt":{"rendered":"<p><strong><span style=\"text-decoration: underline;\">API (Active Pharmaceutical Ingredients) used for Medicinal Purpose<\/span><\/strong><\/p>\n<p>GMP-grade Nicotine with \u226599% purity, suitable for NRT formulations and analytical applications. Supplied with CoA, USDMF\/CEP support, and global export readiness. Available in R&amp;D and commercial-scale quantities.<\/p>","protected":false},"featured_media":186490,"comment_status":"open","ping_status":"closed","template":"","meta":{"rank_math_lock_modified_date":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ep_exclude_from_search":false},"product_cat":[316,764],"product_tag":[],"class_list":{"0":"post-188466","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-pharma-ingredients-raw-materials","7":"product_cat-api-active-pharmaceutical-ingredients-2","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","11":"ast-product-gallery-layout-vertical","12":"ast-product-gallery-with-no-image","13":"ast-magnify-disabled","14":"ast-product-tabs-layout-distributed","16":"first","17":"instock","18":"shipping-taxable","19":"purchasable","20":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/product\/188466","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/comments?post=188466"}],"version-history":[{"count":2,"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/product\/188466\/revisions"}],"predecessor-version":[{"id":1738785,"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/product\/188466\/revisions\/1738785"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/media\/186490"}],"wp:attachment":[{"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/media?parent=188466"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/product_cat?post=188466"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pharmint.net\/ar\/wp-json\/wp\/v2\/product_tag?post=188466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}